BPC-157: what does the evidence actually show?
BPC-157 has broad preclinical research interest, but the human evidence question remains unresolved. Here is what the evidence actually shows.
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Deep-dive compound guides and peptide research overviews
MG53: why your muscle stem cells stop waking up, and what the research says about fixing it
New research identifies MG53 (TRIM72) as a key regulator of muscle stem cell activation in ageing, and a promising therapeutic target for sarcopenia. Here’s what the science shows.
NAD+: the longevity molecule that just got its biggest scientific endorsement yet
25+ scientists published a coordinated expert review in Nature Aging confirming NAD+ as a central target in aging research. Here’s what the evidence says about NMN, NR, and the case for NAD+ augmentation.
VITAL-H: the $38 million human trial that could finally prove longevity drugs work
VITAL-H is a $38 million federally funded trial testing rapamycin, semaglutide, and dapagliflozin in 700–1,000 healthy adults aged 60–65. Here’s what it’s measuring and why it matters.
Thymalin and the Khavinson bioregulator peptides: 40 years of aging research most people haven’t read
Thymalin, Pinealon, and Vilon are ultra-short bioregulator peptides developed over 40 years by Vladimir Khavinson. Here’s what the clinical data shows.
GHK-Cu: the copper peptide with 50 years of research behind it
GHK-Cu is one of the most-studied peptides in existence. Here’s what five decades of research actually shows — mechanism, findings, and where the science stands in 2026.
The peptide boom: what The Atlantic got right — and where the story gets more complicated
For laboratory and research use only. The Atlantic published a feature today on the underground peptide market — part of the wave of mainstream coverage that’s followed the GLP-1 boom and the broader emergence of peptide compounds in public conversation. It’s serious journalism. It deserves a serious response: one that engages with what it got […]
Bystander senescence: how senescent cells spread and what it means for senotherapy research
For laboratory and research use only. Introduction Cellular senescence is one of the more active areas in ageing biology right now. Senescent cells — those that have permanently exited the cell cycle — accumulate with age and are associated with tissue dysfunction across organ systems. The standard picture is of senescent cells as isolated problem […]
Elamipretide (SS-31): the first FDA-approved mitochondrial peptide
On September 19, 2025, a four-amino-acid peptide became the first approved drug to directly target the inside of a mitochondrion. That sentence probably doesn’t sound as consequential as it is. So let’s unpack it. — ## What is elamipretide? Elamipretide — also known as SS-31, MTP-131, and by the brand name Stealth — is a […]
TB-500 (Thymosin Beta-4): what the research actually shows
A comprehensive review of TB-500 (Thymosin Beta-4) research — covering wound healing, cardiac repair, musculoskeletal and neurological studies with real data from published trials.